| The ratio of monomeric to aggregated forms of Aβ40 and Aβ42 is an important determinant of amyloid-β aggregation, fibrillogenesis, and toxicity A Jan, O Gokce, R Luthi-Carter, HA Lashuel Journal of Biological Chemistry 283 (42), 28176-28189, 2008 | 320 | 2008 |
| Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research A Jan, DM Hartley, HA Lashuel Nature protocols 5 (6), 1186-1209, 2010 | 288 | 2010 |
| Aβ42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Aβ42 species A Jan, O Adolfsson, I Allaman, AL Buccarello, PJ Magistretti, A Pfeifer, ... Journal of Biological Chemistry 286 (10), 8585-8596, 2011 | 201 | 2011 |
| The prion-like spreading of alpha-synuclein in parkinson’s disease: Update on models and hypotheses A Jan, NP Gonçalves, CB Vaegter, PH Jensen, N Ferreira International journal of molecular sciences 22 (15), 8338, 2021 | 67 | 2021 |
| Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation H Kroth, A Ansaloni, Y Varisco, A Jan, N Sreenivasachary, ... Journal of Biological Chemistry 287 (41), 34786-34800, 2012 | 64 | 2012 |
| Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity A Jan, B Jansonius, A Delaidelli, F Bhanshali, YA An, N Ferreira, ... Acta neuropathologica communications 6, 1-17, 2018 | 59 | 2018 |
| eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response A Jan, B Jansonius, A Delaidelli, SP Somasekharan, F Bhanshali, ... Acta Neuropathologica 133, 101-119, 2017 | 52 | 2017 |
| Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain N Ferreira, NP Gonçalves, A Jan, NM Jensen, A van der Laan, S Mohseni, ... Acta neuropathologica communications 9, 1-17, 2021 | 50 | 2021 |
| Direct intracerebral delivery of a miR-33 antisense oligonucelotide into mouse brain increases brain ABCA1 expression. MRH A Jan, JM Karasinska, MH Kang, W de Haan , P Ruddle, A Kaur, C Connolly ... Neuroscience Letters, 2015 | 33 | 2015 |
| MYCN amplified neuroblastoma requires the mRNA translation regulator eEF2 kinase to adapt to nutrient deprivation A Delaidelli, GL Negri, A Jan, B Jansonius, A El-Naggar, JKM Lim, ... Cell Death & Differentiation 24 (9), 1564-1576, 2017 | 30 | 2017 |
| Translational control in brain pathologies: biological significance and therapeutic opportunities A Delaidelli, A Jan, J Herms, PH Sorensen Acta Neuropathologica 137, 535-555, 2019 | 28 | 2019 |
| α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response A Delaidelli, M Richner, L Jiang, A van der Laan, ... Acta Neuropathologica Communications 9, 1-16, 2021 | 21 | 2021 |
| GLP-1 receptor agonists in neurodegeneration: neurovascular unit in the spotlight G Monti, D Gomes Moreira, M Richner, HAM Mutsaers, N Ferreira, A Jan Cells 11 (13), 2023, 2022 | 15 | 2022 |
| Gene transfer in rodent nervous tissue following hindlimb intramuscular delivery of recombinant adeno-associated virus serotypes AAV2/6, AAV2/8, and AAV2/9 A Jan, M Richner, CB Vægter, JR Nyengaard, PH Jensen Neuroscience Insights 14, 1179069519889022, 2019 | 9 | 2019 |
| Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy N Ferreira, M Richner, A van der Laan, I Bergholdt Jul Christiansen, ... Brain Communications 3 (2), fcab104, 2021 | 7 | 2021 |
| a beginner’s guide into curated analyses of open access datasets for biomarker discovery in neurodegeneration D Gomes Moreira, A Jan Scientific Data 10 (1), 432, 2023 | | 2023 |
| Biomarkers in neurodegeneration: A beginner’s guide into curated analyses using publicly available datasets DG Moreira, A Jan | | 2023 |
| Correction to: Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy N Ferreira, M Richner, A van der Laan, IB Jul Christiansen, CB Vægter, ... Brain Communications 4 (2), fcac067, 2022 | | 2022 |
| Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion M Richner, NP Gonçalves, PH Jensen, JR Nyengaard, CB Vægter, A Jan STAR protocols 3 (1), 101181, 2022 | | 2022 |
| α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant A Delaidelli, M Richner, L Jiang, A van der Laan, IBJ Christiansen, ... | | 2021 |
Hilal LashuelEPFLE-mail confirmado em epfl.ch
