UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development K Agger, PAC Cloos, J Christensen, D Pasini, S Rose, J Rappsilber, ... Nature 449 (7163), 731-734, 2007 | 1538 | 2007 |
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions AP Bracken, N Dietrich, D Pasini, KH Hansen, K Helin Genes & development 20 (9), 1123-1136, 2006 | 1528 | 2006 |
EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer AP Bracken, D Pasini, M Capra, E Prosperini, E Colli, K Helin The EMBO journal, 2003 | 1450 | 2003 |
Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity D Pasini, AP Bracken, MR Jensen, EL Denchi, K Helin The EMBO journal 23 (20), 4061-4071, 2004 | 1069 | 2004 |
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ... Genes & development 21 (5), 525-530, 2007 | 1027 | 2007 |
A model for transmission of the H3K27me3 epigenetic mark KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ... Nature cell biology 10 (11), 1291-1300, 2008 | 820 | 2008 |
The polycomb group protein Suz12 is required for embryonic stem cell differentiation D Pasini, AP Bracken, JB Hansen, M Capillo, K Helin Molecular and cellular biology, 2007 | 806 | 2007 |
RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3 J Christensen, K Agger, PAC Cloos, D Pasini, S Rose, L Sennels, ... Cell 128 (6), 1063-1076, 2007 | 639 | 2007 |
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells D Pasini, PAC Cloos, J Walfridsson, L Olsson, JP Bukowski, JV Johansen, ... Nature 464 (7286), 306-310, 2010 | 625 | 2010 |
Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity KJ Ferrari, A Scelfo, SG Jammula, A Cuomo, I Barozzi, A Stützer, ... Molecular cell 53 (1), 49-62, 2014 | 528 | 2014 |
Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor N Herranz, D Pasini, VM Díaz, C Francí, A Gutierrez, N Dave, M Escriva, ... Molecular and cellular biology 28 (15), 4772-4781, 2008 | 510 | 2008 |
Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity D Danovi, E Meulmeester, D Pasini, D Migliorini, M Capra, R Frenk, ... Molecular and cellular biology, 2004 | 419 | 2004 |
Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes D Pasini, M Malatesta, HR Jung, J Walfridsson, A Willer, L Olsson, ... Nucleic acids research 38 (15), 4958-4969, 2010 | 411 | 2010 |
Polycomb complexes act redundantly to repress genomic repeats and genes M Leeb, D Pasini, M Novatchkova, M Jaritz, K Helin, A Wutz Genes & development 24 (3), 265-276, 2010 | 397 | 2010 |
Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells P Vella, A Scelfo, SG Jammula, F Chiacchiera, K Williams, A Cuomo, ... Molecular cell 49 (4), 645-656, 2013 | 368 | 2013 |
Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2 D Pasini, KH Hansen, J Christensen, K Agger, PAC Cloos, K Helin Genes & development 22 (10), 1345-1355, 2008 | 360 | 2008 |
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia R Villa, D Pasini, A Gutierrez, L Morey, M Occhionorelli, E Viré, ... Cancer cell 11 (6), 513-525, 2007 | 286 | 2007 |
Histone H2AK119 mono-ubiquitination is essential for polycomb-mediated transcriptional repression S Tamburri, E Lavarone, D Fernández-Pérez, E Conway, M Zanotti, ... Molecular cell 77 (4), 840-856. e5, 2020 | 273 | 2020 |
Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland EL Denchi, C Attwooll, D Pasini, K Helin Molecular and cellular biology 25 (7), 2660-2672, 2005 | 236 | 2005 |
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernández-Pérez, C Isella, ... Cell metabolism 28 (6), 848-865. e6, 2018 | 218 | 2018 |