Sebastian Hiller

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Gerhard WagnerHarvard Medical SchoolVerified email at hms.harvard.edu
Björn M. BurmannAssociate Professor, Department of Chemistry & Molecular Biology, Wallenberg Centre (WCMTM)Verified email at gu.se
Petr BrozFull Professor, Department of Biochemistry, University of LausanneVerified email at unil.ch
Daniel J MullerETH Zurich, Department of Biosystems Science and EngineeringVerified email at bsse.ethz.ch
Timm MaierBiozentrum, University of BaselVerified email at unibas.ch
Roman P. JakobUniversity of Basel,Verified email at unibas.ch
Henning StahlbergProfessor for Physics, EPFL, SwitzerlandVerified email at epfl.ch
Vladislav Y OrekhovDepartment of Chemistry and Molecular Biology, University of GothenburgVerified email at nmr.gu.se
Sebastian RühlSenior Researcher at T3 Pharmaceuticals AGVerified email at stjude.org
Rosalie HeiligBeatson Institute for Cancer ResearchVerified email at glasgow.ac.uk
Urs JenalBiozentrum - University of BaselVerified email at unibas.ch
Badri N DubeyStaff Scientist, Centre for Structural Systems Biology (CSSB) Deutsches Elektronen-SynchrotronVerified email at desy.de
Tim SharpeUniversity of BaselVerified email at unibas.ch
Elia AgustoniUniversity of BaselVerified email at unibas.ch
Kim LewisUniversity Distinguished Professor, Northeastern UniversityVerified email at neu.edu
Peter BondBII A*STARVerified email at bii.a-star.edu.sg
Parthasarathi RathSenior Scientist, R&D Discovery Sciences, AstraZeneca-SwedenVerified email at astrazeneca.com
Guillaume MasBiozentrum - University BaselVerified email at unibas.ch
Lichun HeProf. Innovation Academy for Precision Measurement Science and Technology, CASVerified email at apm.ac.cn
Seyed Majed ModaresiPostdoctoral researcher, Biozentrum, University of BaselVerified email at unibas.ch

Sebastian Hiller

Professor for Structural Biology and Biophysics, Biozentrum, University Basel, Switzerland

Verified email at unibas.ch

Structural Biology NMR Spectroscopy


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GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO Journal 35 (16), 1766-1778, 2016	1064	2016
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles S Hiller, RG Garces, TJ Malia, VY Orekhov, M Colombini, G Wagner Science 321 (5893), 1206-1210, 2008	763	2008
A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019	615	2019
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016	406	2016
ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature communications 7 (1), 11929, 2016	375	2016
The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice R Heilig, MS Dick, L Sborgi, E Meunier, S Hiller, P Broz European journal of immunology 48 (4), 584-592, 2018	371	2018
Automated projection spectroscopy (APSY) S Hiller, F Fiorito, K Wüthrich, G Wider Proceedings of the National Academy of Sciences of the United States of …, 2005	279	2005
Chimeric peptidomimetic antibiotics against Gram-negative bacteria A Luther, M Urfer, M Zahn, M Müller, SY Wang, M Mondal, A Vitale, ... Nature 576 (7787), 452-458, 2019	275	2019
Mechanism of membrane pore formation by human gasdermin‐D E Mulvihill, L Sborgi, SA Mari, M Pfreundschuh, S Hiller, DJ Müller The EMBO journal 37 (14), e98321, 2018	246	2018
Regulation of α-synuclein by chaperones in mammalian cells BM Burmann, JA Gerez, I Matečko-Burmann, S Campioni, P Kumari, ... Nature 577 (7788), 127-132, 2020	218	2020
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains C Suzuki, RG Garces, KA Edmonds, S Hiller, SG Hyberts, A Marintchev, ... Proceedings of the National Academy of Sciences 105 (9), 3274-3279, 2008	213	2008
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs T Raschle, S Hiller, TY Yu, AJ Rice, T Walz, G Wagner Journal of the American Chemical Society 131 (49), 17777-17779, 2009	204	2009
Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication C Lori, S Ozaki, S Steiner, R Böhm, S Abel, BN Dubey, T Schirmer, ... Nature 523 (7559), 236-239, 2015	203	2015
A Proton‐Detected 4D Solid‐State NMR Experiment for Protein Structure Determination M Huber, S Hiller, P Schanda, M Ernst, A Böckmann, R Verel, BH Meier ChemPhysChem 12 (5), 915-918, 2011	192	2011
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy L Sborgi, F Ravotti, VP Dandey, MS Dick, A Mazur, S Reckel, M Chami, ... Proceedings of the National Academy of Sciences 112 (43), 13237-13242, 2015	170	2015
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase H Kaur, RP Jakob, JK Marzinek, R Green, Y Imai, JR Bolla, E Agustoni, ... Nature 593 (7857), 125-129, 2021	161	2021
HP1(Swi6) Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts C Keller, R Adaixo, R Stunnenberg, KJ Woolcock, S Hiller, M Bühler Molecular Cell, 2012	159	2012
NMR structure of the apoptosis-and inflammation-related NALP1 pyrin domain S Hiller, A Kohl, F Fiorito, T Herrmann, G Wider, J Tschopp, MG Grütter, ... Structure 11 (10), 1199-1205, 2003	159	2003
Conformation and dynamics of the periplasmic membrane-protein–chaperone complexes OmpX–Skp and tOmpA–Skp BM Burmann, C Wang, S Hiller Nature Structural and Molecular Biology 20 (11), 1265, 2013	155	2013
Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis MK Ried, R Wild, J Zhu, J Pipercevic, K Sturm, L Broger, RK Harmel, ... Nature communications 12 (1), 384, 2021	145	2021

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